Hockemeyer, Dirk F. : rechercher sur Z-Library

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Articles (40)
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1

Genome-edited human stem cells expressing fluorescently labeled endocytic markers allow quantitative analysis of clathrin-mediated endocytosis during differentiation

Dambournet, Daphné, Sochacki, Kem A., Cheng, Aaron T., Akamatsu, Matthew, Taraska, Justin W., Hockemeyer, Dirk, Drubin, David G.

Journal:

The Journal of Cell Biology

Année:

2018

Langue:

english

Fichier:

PDF, 1.72 MB

english, 2018

2

Controlled Cycling and Quiescence Enables Efficient HDR in Engraftment-Enriched Adult Hematopoietic Stem and Progenitor Cells

Shin, Jiyung J., SchrÃ¶der, Markus S., Caiado, Francisco, Wyman, Stacia K., Bray, Nicolas L., Bordi, Matteo, Dewitt, Mark A., Vu, Jonathan T., Kim, Won-Tae, Hockemeyer, Dirk, Manz, Markus G., Corn, Ja

Journal:

Année:

2020

Fichier:

PDF, 3.02 MB

2020

3

Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression

Wang, Zhigao, Wang, Da-Zhi, Hockemeyer, Dirk, McAnally, John, Nordheim, Alfred, Olson, Eric N.

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 452 KB

english, 2004

4

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

Hockemeyer, Dirk, Soldner, Frank, Beard, Caroline, Gao, Qing, Mitalipova, Maisam, DeKelver, Russell C, Katibah, George E, Amora, Ranier, Boydston, Elizabeth A, Zeitler, Bryan

Journal:

Nature Biotechnology

Année:

2009

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2009

5

Corrigendum: Telomere protection by mammalian Pot1 requires interaction with Tpp1

Hockemeyer, Dirk, Palm, Wilhelm, Else, Tobias, Daniels, Jan-Peter, Takai, Kaori K, Ye, Jeffrey Z-S, Keegan, Catherine E, de Lange, Titia, Hammer, Gary D

Journal:

Nature Structural and Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 73 KB

english, 2009

6

Telomere protection by mammalian Pot1 requires interaction with Tpp1

Hockemeyer, Dirk, Palm, Wilhelm, Else, Tobias, Daniels, Jan-Peter, Takai, Kaori K, Ye, Jeffrey Z-S, Keegan, Catherine E, de Lange, Titia, Hammer, Gary D

Journal:

Nature Structural and Molecular Biology

Année:

2007

Langue:

english

Fichier:

PDF, 575 KB

english, 2007

7

SRF regulates Bcl-2 expression and promotes cell survival during murine embryonic development

Schratt, Gerhard, Philippar, Ulrike, Hockemeyer, Dirk, Schwarz, Heinz, Alberti, Siegfried, Nordheim, Alfred

Journal:

The EMBO Journal

Année:

2004

Langue:

english

Fichier:

PDF, 544 KB

english, 2004

8

POT1 protects telomeres from a transient DNA damage response and determines how human chromosomes end

Hockemeyer, Dirk, Sfeir, Agnel J, Shay, Jerry W, Wright, Woodring E, de Lange, Titia

Journal:

The EMBO Journal

Année:

2005

Langue:

english

Fichier:

PDF, 371 KB

english, 2005

9

Genetic engineering of human pluripotent cells using TALE nucleases

Hockemeyer, Dirk, Wang, Haoyi, Kiani, Samira, Lai, Christine S, Gao, Qing, Cassady, John P, Cost, Gregory J, Zhang, Lei, Santiago, Yolanda, Miller, Jeffrey C

Journal:

Nature Biotechnology

Année:

2011

Langue:

english

Fichier:

PDF, 467 KB

english, 2011

10

Recent Expansion of the Telomeric Complex in Rodents: Two Distinct POT1 Proteins Protect Mouse Telomeres

Dirk Hockemeyer, Jan-Peter Daniels, Hiroyuki Takai, Titia de Lange

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2006

11

Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors

Frank Soldner, Dirk Hockemeyer, Caroline Beard, Qing Gao, George W. Bell, Elizabeth G. Cook, Gunnar Hargus, Alexandra Blak, Oliver Cooper, Maisam Mitalipova, Ole Isacson, Rudolf Jaenisch

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 2.99 MB

english, 2009

12

Mammalian Telomeres Resemble Fragile Sites and Require TRF1 for Efficient Replication

Agnel Sfeir, Settapong T. Kosiyatrakul, Dirk Hockemeyer, Sheila L. MacRae, Jan Karlseder, Carl L. Schildkraut, Titia de Lange

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 1.85 MB

english, 2009

13

Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors

Frank Soldner, Dirk Hockemeyer, Caroline Beard, Qing Gao, George W. Bell, Elizabeth G. Cook, Gunnar Hargus, Alexandra Blak, Oliver Cooper, Maisam Mitalipova, Ole Isacson, Rudolf Jaenisch

Journal:

Année:

2009

Fichier:

PDF, 33 KB

2009

14

Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations

Frank Soldner, Josée Laganière, Albert W. Cheng, Dirk Hockemeyer, Qing Gao, Raaji Alagappan, Vikram Khurana, Lawrence I. Golbe, Richard H. Myers, Susan Lindquist, Lei Zhang, Dmitry Guschin, Lauren K.

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 2.86 MB

english, 2011

15

Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations

Frank Soldner, Josée Laganière, Albert W. Cheng, Dirk Hockemeyer, Qing Gao, Raaji Alagappan, Vikram Khurana, Lawrence I. Golbe, Richard H. Myers, Susan Lindquist, Lei Zhang, Dmitry Guschin, Lauren K.

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 417 KB

english, 2011

16

A Drug-Inducible System for Direct Reprogramming of Human Somatic Cells to Pluripotency

Dirk Hockemeyer, Frank Soldner, Elizabeth G. Cook, Qing Gao, Maisam Mitalipova, Rudolf Jaenisch

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 1.53 MB

english, 2008

17

Chromatin Structure and Gene Expression Programs of Human Embryonic and Induced Pluripotent Stem Cells

Matthew G. Guenther, Garrett M. Frampton, Frank Soldner, Dirk Hockemeyer, Maya Mitalipova, Rudolf Jaenisch, Richard A. Young

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 1.44 MB

english, 2010

18

Global Transcriptional and Translational Repression in Human-Embryonic-Stem-Cell-Derived Rett Syndrome Neurons

Li, Yun, Wang, Haoyi, Muffat, Julien, Cheng, Albert W., Orlando, David A., Lovén, Jakob, Kwok, Show-ming, Feldman, Danielle A., Bateup, Helen S., Gao, Qing, Hockemeyer, Dirk, Mitalipova, Maisam, Lewis

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 3.27 MB

english, 2013

19

Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulation

Sexton, Alec N., Regalado, Samuel G., Lai, Christine S., Cost, Gregory J., O’Neil, Colleen M., Urnov, Fyodor D., Gregory, Philip D., Jaenisch, Rudolf, Collins, Kathleen, Hockemeyer, Dirk

Journal:

Genes & Development

Année:

2014

Langue:

english

Fichier:

PDF, 1.92 MB

english, 2014

20

Essentials of Stem Cell Biology || Direct Reprogramming of Somatic Cells to a Pluripotent State

Hockemeyer, Dirk

Année:

2009

Langue:

english

Fichier:

PDF, 97 KB

english, 2009

21

TALEN Gene Knockouts Reveal No Requirement for the Conserved Human Shelterin Protein Rap1 in Telomere Protection and Length Regulation

Kabir, Shaheen, Hockemeyer, Dirk, de Lange, Titia

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 2.51 MB

english, 2014

22

Genome editing 101: let's go digital

Forster, Ryan, Hockemeyer, Dirk

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 261 KB

english, 2014

23

Control of telomerase action at human telomeres

Hockemeyer, Dirk, Collins, Kathleen

Journal:

Nature Structural and Molecular Biology

Année:

2015

Langue:

english

Fichier:

PDF, 541 KB

english, 2015

24

Human stem cell-based disease modeling: prospects and challenges

Johnson, Joshua Z, Hockemeyer, Dirk

Journal:

Current Opinion in Cell Biology

Année:

2015

Langue:

english

Fichier:

PDF, 528 KB

english, 2015

25

Deletion of the de novo DNA methyltransferase Dnmt3a promotes lung tumor progression

Qing Gao, Eveline J. Steine, M. Inmaculada Barrasa, Dirk Hockemeyer, Mathias Pawlak, Dongdong Fu, Seshamma Reddy, George W. Bell and Rudolf Jaenisch

Journal:

Proceedings of the National Academy of Sciences

Année:

2011

Langue:

english

Fichier:

PDF, 1.88 MB

english, 2011

26

Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats

Gunnar Hargus, oliver Cooper, Michela Deleidi, Adam Levy, Kristen Lee, Elizabeth Marlow, Alyssa Yow, Frank Soldner, Dirk Hockemeyer, Penelope J. Hallett, Teresia Osbron, Rudolf Jaenisch and Ole lsacso

Journal:

Proceedings of the National Academy of Sciences

Année:

2010

Langue:

english

Fichier:

PDF, 1.89 MB

english, 2010

27

Induced Pluripotent Stem Cells Meet Genome Editing

Hockemeyer, Dirk, Jaenisch, Rudolf

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 1.73 MB

english, 2016

28

Endogenous TERT N-terminal tagging affects human telomerase function at telomeres in vivo

Chiba, Kunitoshi, Vogan, Jacob M., Wu, Robert A., Gill, Manraj S., Zhang, Xiaozhu, Collins, Kathleen, Hockemeyer, Dirk

Journal:

Molecular and Cellular Biology

Année:

2016

Langue:

english

Fichier:

PDF, 7.55 MB

english, 2016

29

efficient replication

Sfeir, Agnel, Kosiyatrakul, Settapong T, Hockemeyer, Dirk, Macrae, Sheila L, Schildkraut, Carl L, Lange, Titia De

Année:

2010

Langue:

english

Fichier:

PDF, 4.68 MB

english, 2010

30

Mutations in the promoter of the telomerase gene TERT contribute to tumorigenesis by a two-step mechanism

Chiba, Kunitoshi, Lorbeer, Franziska K., Shain, A. Hunter, McSwiggen, David T., Schruf, Eva, Oh, Areum, Ryu, Jekwan, Darzacq, Xavier, Bastian, Boris C., Hockemeyer, Dirk

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 2.36 MB

english, 2017

31

Establishment of Genome-edited Human Pluripotent Stem Cell Lines: From Targeting to Isolation

Blair, John D., Bateup, Helen S., Hockemeyer, Dirk F.

Journal:

Journal of Visualized Experiments

Année:

2016

Langue:

english

Fichier:

PDF, 1.49 MB

english, 2016

32

Widespread Translational Remodeling during Human Neuronal Differentiation

Blair, John D., Hockemeyer, Dirk, Doudna, Jennifer A., Bateup, Helen S., Floor, Stephen N.

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 2.53 MB

english, 2017

33

Transgene Excision Has No Impact on In Vivo Integration of Human iPS Derived Neural Precursors

Major, Tamara, Menon, Jayanthi, Auyeung, Gordon, Soldner, Frank, Hockemeyer, Dirk, Jaenisch, Rudolf, Tabar, Viviane, Silver, Debra L.

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 5.81 MB

english, 2011

34

Cancer-associated TERT promoter mutations abrogate telomerase silencing

Chiba, Kunitoshi, Johnson, Joshua Z, Vogan, Jacob M, Wagner, Tina, Boyle, John M, Hockemeyer, Dirk

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 5.91 MB

english, 2015

35

Genetically engineered human cortical spheroid models of tuberous sclerosis

Blair, John D., Hockemeyer, Dirk, Bateup, Helen S.

Journal:

Nature Medicine

Année:

2018

Langue:

english

Fichier:

PDF, 3.49 MB

english, 2018

36

4D cell biology: big data image analytics and lattice light-sheet imaging reveal dynamics of clathrin-mediated endocytosis in stem cell derived intestinal organoids

Schöneberg, Johannes, Dambournet, Daphné, Liu, Tsung-Li, Forster, Ryan, Hockemeyer, Dirk, Betzig, Eric, Drubin, David G., Barber, Diane L

Journal:

Molecular Biology of the Cell

Année:

2018

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2018

37

4D Cell Biology: Big Data Image Analytics and Lattice Light-Sheet Imaging Reveal Dynamics of Clathrin-Mediated Endocytosis in Stem Cell-Derived Intestinal Organoids

Schöneberg, Johannes, Dambournet, Daphné, Liu, Tsung-Li, Forster, Ryan, Hockemeyer, Dirk, Betzig, Eric, Drubin, David G.

Journal:

Biophysical Journal

Année:

2019

Langue:

english

Fichier:

PDF, 46 KB

english, 2019

38

TERT promoter mutations and telomeres during tumorigenesis

Lorbeer, Franziska K, Hockemeyer, Dirk

Journal:

Current Opinion in Genetics & Development

Année:

2020

Langue:

english

Fichier:

PDF, 532 KB

english, 2020

39

Analysis of muntjac deer genome and chromatin architecture reveals rapid karyotype evolution

Mudd, Austin B., Bredeson, Jessen V., Baum, Rachel, Hockemeyer, Dirk, Rokhsar, Daniel S.

Journal:

Communications Biology

Année:

2020

Fichier:

PDF, 1.48 MB

2020

40

Telomere length set point regulation in human pluripotent stem cells critically depends on the shelterin protein TPP1

Boyle, John M., Hennick, Kelsey M., Regalado, Samuel G., Vogan, Jacob M., Zhang, Xiaozhu, Collins, Kathleen, Hockemeyer, Dirk, Lechler, Terry

Journal:

Molecular Biology of the Cell

Année:

2020

Fichier:

PDF, 1.50 MB

2020